I think I am going to switch from Zoloft to Celexa. I KNOW that we all are different & every medicine will affect us on a different level, but is there a difference between the two? I hope I don't have the same side effects I had on Zoloft. All SSRIs are appropriate to be used as an anxiety treatment, despite being classed as an anti depressant. Instead of YOU deciding which med you want, you're better off explaining to your doc what has been going on, and see what he recommends. While two meds might both be SSRIs, they all work a little differently in their mechanism of action. The end result is the same (an increased amount of serotonin in the brain).how you get there is different with each med, hence why there are so many varying experiences. Cymbalta tends to be a bit activating, so that may not be the best choice, ask your doctor about it. I will give this 4 weeks, as my doctor suggested to see if this is the one for me. I have never experience side effects from a drug the first day..has always taken at least three days before I noticed any of them, so I'm wondering if you may actually be experiencing withdrawal effects from the Zoloft. sildenafil usa Citalopram is a ssri medication used to treat anxiety and depression disorders, it's also used to treat ptsd and ocd. Side effects; sedation, minor temporary stomach issues, delayed orgasm in males and rarely weight gain. It is Celexa (citalopram ) is a antidepressant that works mainly on the serotonin metabolism wellbutrin (bupropion) works in the dopaminergic circuit . They can be combined for added effect or decrease of side effects of serotonin related antidepressants such as decresed libido. Read more See 2 more doctor answers Both are selective serotonin reuptake inhibitors, or ssris, a fancy way of saying they help your brain hold onto and use more of the serotonin it has. Serotonin is one of the chemicals in your body related to happy things, like food, sex, and sleep (which is why the side effects often affect these issues). Read more See 1 more doctor answer Some chemicals, like Celexa have 2 forms which are mirror images of each other. Celexa, prozac, Paxil (paroxetine) are also in class. (like your hands) chemists wil refer to them as left or right sided versions. While Celexa includes both forms, Lexapro (escitalopram) only contains one (the left handed version). Since these drugs act on receptors in the nervous system, like keys in a lock, the right and left handed molecules have some different effects. Read more See 1 more doctor answer Are different in many ways. Viagra therapy Valtrex side effects itching How to use dapoxetine Celexa citalopram is good for treating depression and anxiety. 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