Phenobarbital is a long-acting barbiturate typically prescribed to control seizures. In some circumstances, it is used in treating withdrawal and for other purposes. Knowing how it acts in your system and for how long can help you understand the precautions to take to avoid dangerous drug interactions and possible overdoses. Phenobarbital can be administered as an injection, a liquid elixir, or tablets. Each has their own speed of taking effect and appropriate dosages. Tablets or elixirs begin to act in 30 to 60 minutes, and their duration lasts for 5 to 12 hours, depending on the dosage and individual metabolism. The plasma half-life of phenobarbital in adults is an average of about 79 hours and 110 hours in children. viagra sale learn from me get sober stay that way aint worth it. 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