It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Plaquenil pill side effect Biaxin and plaquenil lyme disease Hydroxychloroquine and the immune system. Just wondered if anyone can tell me whether hydroxy suppresses the immune system. And if so, to what extent. I know it's not as harsh as some of the other drugs but just wondered what people's experiences are. IF Plaquinil hydroxychloroquine is an immunosuppressant, shouldn't doctors inform their patients about this as a 'potential' side effect prior to prescribing the drug? This is NOT a litigious query, but an honest question for future patients. My husband's a very intelligent man; he asks questions and talks with his doctors. Immunosuppressive effects of hydroxychloroquine and artemisinin combination therapy via the nuclear factor-κB signaling pathway in lupus nephritis mice. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Is hydroxychloroquine an immunosuppressive Hydroxychloroquine and the immune system Hi everyone., Do either hydroxychol/Plaquenil put you at risk for greater. Plaquenil sunburnEye update plaquenilCan plaquenil cause a positive nicotine urine testChloroquine and digoxinChloroquin function in lysosome Our Plaquenil hydroxychloroquine Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Immunosuppressive effects of hydroxychloroquine and.. Is Plaquenil a immunosuppressant drug ? Autoimmune.. Hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Definition NCI A 4-aminoquinoline with immunosuppressive, antiautophagy, and antimalarial activities. Although the precise mechanism of action is unknown, hydroxychloroquine may suppress immune function by interfering with the processing and presentation of antigens and the production of cytokines. Hydroxychloroquine may increase the immunosuppressive activities of Cyclosporine. Cymarin The serum concentration of Cymarin can be increased when it is combined with Hydroxychloroquine.