I have been on plaquenil for about 10 weeks now without much success. I have had the sickness to my stomach and not felt like me including exhausted but it's not as bad as I feared. My hair is coming out slightly Not in clumps are anything, just a little here or there. My doctor said if I don't feel better in a few more weeks, we could switch my medicine. Really though in order not to have worse things happen it is what we have to do. I switched back to cymbalta three days ago and have experienced huge relief. Chloroquine and aspirin Hydroxychloroquine mechanism of action in sle Quinacrine can be used together with either Plaquenil or its stronger version Aralen chloroquine for a highly effective combination as the two work together each enhancing the effects of the other. Quinacrine is especially well known for its energising effects & fatigue reduction. When I asked him if I should stay home from work and pull my kids out of school, he said it may be an overreaction, but since we don’t really know, my health comes first. Make sure you’re taking your Vitamin D I take 50000iu/once a week. Unrelated to Covid-19 My lupus is currently attacking my lungs. Unfortunately, retinal damage caused by Aralen may be irreversible, but this medication is rarely prescribed anymore for lupus. Do not smoke while taking anti-malarial medications, since smoking actually reduces the benefits of these drugs. In fact, people with lupus should not smoke at all due to their increased risk of cardiovascular disease. Vitamin B-12 might help with the hair, ask your doctor about that, well wishes to you and I hope the mtx can help you....((((((((((((((((((((((((((((((((((((((((((((((Jeanneac)))))))))))))))))))))))))))))))))))))))))healing hugz and well wishes and keep us posted on how your doing... Had headaches with the plaquenil so went to the sulfar and predisone. (like i did friday) Take care of yourself and big(((HUGS))) on your journey. He said it would be one that they would have to more closely monitor me on with some blood tests. I was thinking it was methotrexate but I do not want my hair to fall out. It might be coincidence but since on the plaquenil, I have noticed a growth spurt of hair especially at the hairline. Plaquenil made me sick, so I can't take it either, but there are other medicine out there,the doctor's will get you on something that'll help, keep hope..wishes to you and try the methotrexate,to see if it can help... I know it is scary but anything to stop the pain and misfunction of not being able to use my hands or move my knees or not have my ankles cave out and fall. I suspected that I had fibromyalgia on top of the inflammation. I am so relieved but hope I don't start having bad side effects from it like I did before with a very dry mouth and gritting my teeth at night. Plaquenil and quinacrine not working anymore for lupus Treating Lupus With Antimalarial Drugs Woodland Hills Pharmacy, Plaquenil and corona lupus Hydroxychloroquine sulfate vs sodium bicarbonatePlaquenil cessation Today’s AMs are hydroxychloroquine Plaquenil®, chloroquine Aralen®, and quinacrine Atabrine®. Quinacrine is no longer marketed in the U. S.; it can be dispensed by a compounding pharmacy, although insurance companies may not pay for it. The antimalarial quinine was first used to treat cutaneous lupus in 1834. Drug spotlight on hydroxychloroquine Lupus Foundation of.. Treating Lupus with Anti-Malarial Drugs Johns Hopkins.. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. From Malaria to Lupus & RA. Anecdotal reports describing improvement in lupus and rheumatoid arthritis RA by Allied soldiers on long-term quinacrine culminated in the first published report by Page in the Lancet, in 1951. 6 Following this, other papers followed, and the drugs became a mainstay in the treatment of SLE and increasingly prescribed in RA. It has numerous benefits on lupus and in general tends to lower cholesterol for instance. It is interesting that you were first prescribed mepacrine/quinacrine instead of Plaquenil. Mepacrine will do more to battle the fatigue as it is stimulating, Plaquenil is not as helpful in that respect as it is not stimulating. May 07, 2019 plaquenil hydroxychloroquine is commonly used to help keep mild lupus-related problems, such as skin and joint disease, under control. this drug is also effective at preventing lupus flares.