Malaria is a serious but rare disease caused by bites from infected mosquitos. Now the drug is used to treat inflammatory diseases. Ankylosing spondylitis hydroxychloroquine Plaquenil and vision SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Plaquenil is an extremely safe medication but retinal and corneal side effects are possible. Unfortunately, the retinal side effects are largely irreversible and can lead to vision loss. So, it is critical to detect early retinal toxicity in the hopes of limiting the extent of visual loss. Plaquenil and your eyes. A rare side effect of Plaquenil is damage to the eye's retina. The retina is the light-sensitive tissue at the back of the eye. Using Plaquenil for a long period of time may harm the retina, causing serious vision loss. People with retinal damage from Plaquenil are not aware at first that they are losing vision. Some diseases treated with Plaquenil include: Plaquenil lowers your immune system’s ability to cause inflammation. This type of disease occurs when the body's immune system attacks its own healthy tissue. Plaquenil effects on eyes Plaquenil Hydroxychloroquine Side Effects and Adverse. - Total Eye, Plaquinel Related Eye Problems - Fraser Eye Care Center Areas with chloroquine or mefloquine resistanceChloroquine phosphate reef2reef The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. For short-term treatment of acute malaria, adverse effects can include abdominal cramps, diarrhea, heart problems, reduced appetite, headache, nausea and vomiting. Hydroxychloroquine - Wikipedia. What Is Plaquenil? - American Academy of Ophthalmology. How lupus affects the eyes Lupus Foundation of America. Hydroxychloroquine typically is very well tolerated. Serious side effects are rare. The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. Patients using plaquenil may experience important but rare side effects that affect the eyes, including damage to the retina back of the eye, cornea front of the eye, and eyelids. These side effects typically occur on high doses of the medication and increase with duration of use.