Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Home remedies plaquenil hyperpigmentation Teva chloroquine side effects Plaquenil common side effects Plaquenil dosage for psoriatic arthritis The prednisone is a steriod and the plaquenil is a anti malaria drug. The thing with plaquenil for me is that I don't notice much of anything taking it but when I go off then I flare up and then really notice it. I have been taking the plaquinil for about 8 years morning and night and the prednisone off and on. If you take medications such as estrogens or barbiturates with prednisone, drug interactions may potentially occur. These interactions can increase your risk of side effects, affect the level of prednisone in your blood, or decrease the effectiveness of some medications. Although prednisone rarely has a direct interaction with other medications, there is an increased risk of infection when combining prednisone with other medications that affect your immune system. Additionally, when taking prednisone with NSAIDs such as naproxen or ibuprofen, there can be an increased risk of stomach ulcers. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Prednisone and hydroxychloroquine interaction Hydroxychloroquine Side Effects, Dosage, Uses, and More, Prednisone Drug Interactions - eMedTV Health Information. How do i get off the drug plaquenilChloroquine resistant malaria pptPlaquenil sudden tightness neck painChloroquine concentration transfectionChloroquine plus primaquine I started with plaquenil last year, yes it took almost 6 months to get a level in your body, it does help, trust me. I was on Prednisone 7.5 to 10 mg per day, had a bad flair up and I am on 40 mg per day, last Friday the dr.''s told me to go down by 5 mg per week, so from 40mg to 35 mg per day. Prednisone and Plaquenil question" Lupus Community.. Prednisone Deltasone. Prednisone and plaquenil -. Hydroxychloroquine is a disease-modifying anti-rheumatic drug DMARD. It regulates the activity of the immune system, which may be overactive in some conditions. Hydroxychloroquine can modify the underlying disease process, rather than simply treating the symptoms. Digoxin, cyclosporine, and certain beta blockers may cause drug interactions with hydroxychloroquine. This eMedTV segment explores what may happen if these drugs are taken with hydroxychloroquine and lists other drugs that may cause an interaction. Hydroxychloroquine Interactions Avoid taking an antacid or Kaopectate kaolin-pectin within 4 hours before or after you take hydroxychloroquine. Some antacids can make it harder for your body to.