I've been on plaquenil for 6 months for suspected Sjogren's syndrome (I don't have antibodies for Sjorgren's or Lupus but I do have Hashimoto's and have all the symptoms for Sjorgren's so the rheumatologist suggested a trial of plaquenil). Basically I've been on the drug since January and saw the rheumatologist on Wednesday to see how things are going. Chloroquine high creatinine treatment Dose of plaquenil for rheumatoid arthritis Plaquenil for subacute cutaneous lupus O hydroxychloroquine Severe depression and anxiety, overall itching, pain and stiffness increased instead of decreased. First, my mother and sister took plaquenil for lupus with good effect, so I am not just disliking it for no good reason. I also suffer from disabling bipolar disorder. For 25 years, I have gotten hypomanic during spring. Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. Jan 29, 2007 I don't agree with her. of couse some of these symptoms do come with Plaquenil, but the nausea and bad reflux I have had for a very long time BEFORE the Plaquenil. She has given me an oral tablet to take for the itch, steroid cream for the rash, and she was going to give me something to empty my stomach out quicker but we both forgot before my session was finished. I do think it's helped with fatigue and muscle pain but it's hard for me to compare to Xmas as when the improvement is so gradual I think it's really hard to notice on a gradual basis. I *think* I'm improving but it's been a gradual process and I said to him that it's quite hard to tell how much of an improvement I'm feeling. Stopped plaquenil now symptoms have returned Plaquenil Hydroxychloroquine MyPsoriasisTeam, Plaquenil Oral Uses, Side Effects, Interactions, Pictures. Plaquenil e depressione In Stop Sarcoidosis My pulmonist started me on high doses of prednisone in 1999, he would start to decrease, and he would tell me I am not responding to the decrease. Methotrexate and side effects In Stop Sarcoidosis Have just had my second dose of methotrexate and have had side effects already. Side effects to Stopping Plaquenil. - Sarcoidosis - Inspire. Coming Off Plaquenil questions - Sclero Forums MAIN.. Plaquenil Withdrawal – Life As An Anomaly. Hi honey, YES.stopping plaquenil for a couple of days can cause symptoms to arise or get worse.needs to be taken exactly as prescribed. Twice a day, every day. Missing one dose wont make a major difference but skipping more then one, or days absolutely can. Certified integrative health coach Luanna Barker of New York says that RA and lupus patients who have to stop taking Plaquenil can focus on alternative methods of treatment in the interim, until. Return of symptoms. This would be quite variable and it may take days, weeks or months before any relapse occurs. A lot depends on the type and intensity of your original disorder. Did your ANA level fall when you were started on plaquenil? Relapse would most likely consist of return of your original symptoms.