Alternatively, we suggest using this opportunity to take a little break from work and read some of the interesting articles below. Summary Chloroquine is an anti-malarial drug available at pharmacies for people traveling to area with malaria risks. Chloroquine er derived vaculation Chloroquine scheduled drug Mice injected daily with chloroquine showed slower growth and less lung metastasis of subcutaneous melanoma xenografts. However, chloroquine did not suppress the invasion of cultured cancer cells into Matrigel, and lung colonization was not reduced by exposure of cancer cells to chloroquine prior to intravenous injection in mice. Chloroquine, a drug that has historically been used to treat malaria, has recently been combined with a new drug, Tarceva, which kills lung cancer cells. Tarceva only works for some patients, and the cancer almost always becomes resistant after prolonged exposure to the drug. Regulators for cancer chemotherapy. We investigated the potential roles and mechanisms of hydroxychloroquine HCQ in combination with chemotherapy in lung cancer treatment. Methods The effects of combined treatment on non-small cell lung cancer NSCLC were investigated using cell viability assays and animal models. It is one of very few available drugs that inhibits autophagy, a mechanism associated with its anticancer properties. Note: based on a RGCC chemosensitivity analysis I have seen at a German clinic, Hydroxychloroquine has been effective in killing the cancer cells of 5 out 7 patients that were tested. Chloroquine lung cancer Chloroquine inhibits cell growth and induces cell death in., Repurposing Drugs 101 - Chloroquine & Lung Cancer Primaquine and chloroquine are drugs used in the treatment of Chloroquines are expected to have diverse effects on cancer progression. Inhibition of late autophagy can affect cell survival, as well as antigen processing and presentation in the immune system. Co. Dissecting pharmacological effects of chloroquine in cancer.. Hydroxychloroquine induced lung cancer suppression by.. Malaria medicine chloroquine inhibits tumor growth.. Chloroquine CQ has been revealed to exhibit antitumor activity in several human tumors including lung cancer as mono‑ or add‑on therapy. The antitumor effect of CQ appears to depend on the tumor type, stage and genetic context. Apr 11, 2012 Chloroquine as an Anti-autophagic Radiosensitizing Drug in Stage I-III Small Cell Lung Cancer Chloroquine The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.