It is a disabling and painful condition which can lead to substantial loss of mobility due to pain and joint destruction. I've been off it a few days and thankfully my plumbing is back to normal it seems and the huge acne has stopped/gone. The disease is also systemic in that it often also affects many extra-articular tissues throughout the body including the skin, blood vessels, heart, lungs, and... Since I'm a woman I managed to bypass the plumbing problems while on the prednisone (I'm on 30 mg), but you're right, the acne is BAD!! Considering the state my joints are in though, I suppose that's the least of my problems. Plaquenil pill picture Hydroxychloroquine metallic taste Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. Nov 14, 2006 I can tell you that plaquenil is the safest of all of the DMARDs. If you're going to stay on a DMARD for a long time, plaquenil is the one to be on. Best of luck on the plaquenil. Re Plaquenil - Can It Work Quickly? I tried to get on Plaquenil years ago, and couldn't tolerate it, but now I'm thinking there might be a lessor dose I should try. I'm new to the area, so don't have a rheumy yet. My doctor was only able to find it after I requested a MRI of my hands. Of course neither has the prednisone, sulfasalazine, or methotrexate. Hi guys, I was diagnosed with RA in April 08 and I'm 29 years old. I've been on plaquenil for over 4 months and it hasn't done squat for me. How to tell if plaquenil is working Plaquenil Indications, Side Effects, Warnings -, Plaquenil - Atrovent and plaquenil Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Plaquenil Oral Uses, Side Effects, Interactions.. Immune & Autoimmune - Lupus Plaquenil - Can It Work Quickly?. Plaquenil Side Effects on Your Eyes and Vision. Long-term use of Plaquenil is associated with damage to the retina in the eye, the portion of the eyeball that is sensitive to light. It is important to see an ophthalmologist before starting Plaquenil to establish a baseline. And, you should have regular eye screenings the entire time you take the medication. The vast majority of patients on Plaquenil get absolutely no eye problems and you should not be unduly worried or concerned. If you have a good response in your arthritis to the Plaquenil then the benefits of a Plaquenil almost certainly outweigh the small risks to your eyes. Study Raises Questions about Sjogren's and Plaquenil. For many patients with Sjogren's, Plaquenil hydroxychloroquine has long been the go to drug that their doctors prescribe. It is often the first line of attack before other more aggressive therapies are added such as methotrexate or rituximab that have bigger impacts on the immune system.