It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Plaquenil high blood pressure Plaquenil leg swelling The mechanism of action is thought to be anti-inflammatory, but Plaquenil also seems to reduce sensitivity to sunlight. It has also been noted recently that smoking reduces the effectiveness of Plaquenil in treating lupus, thus, smoking cessation should be instituted in all patients taking Plaquenil. More About Autoimmune diseases DERMATOMYOSITIS Hydroxychloroquine treats malaria, systemic lupus erythematosus, rheumatic disorders like rheumatoid arthritis, porphyria cutanea tarda, and Q fever. 1 In 2014, its efficacy to treat Sjögren syndrome was questioned in a double-blind study involving 120 patients over a 48-week period. Mar 17, 2019 Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Hydroxychloroquine for autoimmune diseases Plaquenil Hydroxychloroquine - Side Effects, Dosage, Interactions - Drugs, Hydroxychloroquine - Wikipedia Plasmodium falciparum chloroquine resistance first seen I have been taking plaquenil for uctd for about 6 years or so. Can't live without it. Supposed to take couple months to kick in but worked for me within 2 days. If I miss a dose, I feel it a day and a half later- my legs like lead, really lousy, etc. I am extremely sensitive and responsive to it. Plaquenil for UCTD - Autoimmune diseases - Inspire. Hydroxychloroquine Uses, Dosage & Side Effects -. Hydroxychloroquine Plaquenil and Hair Loss Is my Plaquenil.. Anwar Nassar. Munther Khamashta, in Handbook of Systemic Autoimmune Diseases, 2017. 18.4.8 Hydroxychloroquine. Hydroxychloroquine, an antimalarial drug, is traditionally used in the treatment of SLE. Its effectiveness in treating APS has been previously questioned. Plaquenil hydroxychloroquine is considered an older DMARD disease modifying anti-rheumatic drug. Plaquenil was actually first classified as an antimalarial drug, but it is also used to treat certain rheumatic and autoimmune conditions which are unrelated to malaria. Generally, Plaquenil is a treatment option as monotherapy used alone for mild rheumatoid arthritis or as combination. Hydroxychloroquine also known by its popular brand name Plaquenil is an oral medication that is commonly used to treat a variety of autoimmune diseases including systemic lupus, dermatomyositis, rheumatoid arthritis, Sjogren’s and many other conditions as well. In the field of hair loss, conditions such as lichen planopilaris, frontal fibrosing alopecia and discoid lupus are frequently treated with hydroxychloroquine.