Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Plaquenil (hydroxychloroquine) with all of your drugs and health problems. Plaquenil side effects fatigue Plaquenil staggered dose Sjogrens pronounced 'show-grins' can cause dry mouth, dry eyes, swollen glands and some other interesting fun stuff. Usually starts with the dry mouth and eyes. You'll want to make sure that your daughter has very regular dental.your daughter is on plaquenil, I'm assuming that she is seeing an ophthalmologist too. He should be watching for dry eyes. It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known exactly how the drug works. How to use Plaquenil Hydroxychloroquine is usually taken with food. Lupus, which causes fever, rashes, skin problems, and other symptoms. Rheumatoid arthritis, a condition that causes pain and swelling in the joints of your hands and feet. Sjögren’s syndrome, which causes dry eyes and dry mouth. Plaquenil lowers your immune system’s ability to cause inflammation. For all uses of Plaquenil (hydroxychloroquine): WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Do not start, stop, or change the dose of any drug without checking with your doctor. Can plaquenil cause swelling Swollen feet and plaquenil Anti-Inflammatories., Plaquenil Oral Uses, Side Effects, Interactions. Can plaquenil cause dry mouthDrugs used in chloroquine resistant malariaChloroquine tabletsPlaquenil coughEye plaquenil Lupus arthritis causes pain, stiffness, swelling, tenderness and warmth in your joints. The joints most often affected are the ones farthest from the middle of the body, such as fingers, wrists, elbows, knees, ankles and toes. How Lupus Affects the Muscles, Tendons and Joints Lupus.. What Is Plaquenil? - American Academy of Ophthalmology. What Is Macular Edema? - American Academy of Ophthalmology. Lip swelling is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 month, also take medication Benlysta, and have High blood pressure It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin with or without fever; red or irritated eyes; or sores in your mouth, throat, nose, or eyes. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.