Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Chloroquine effect on gametocytes What is the function of hydroxychloroquine sulfate tablets Find information about common, infrequent and rare side effects of Plaquenil Oral. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. Plaquenil is a drug used to treat Rheumatoid Arthritis and Systemic Lupus Erythematosis. It is a very good drug and gives many patients significant relief from their symptoms. Plaquenil related eye complications are not common. Plaquenil can produce pigment changes in the macula of the retina. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil side effects eyes symptoms Plaquenil Toxicity - Symptoms, Treatment, Risk Factors., Plaquenil Hydroxychloroquine - Side Effects, Dosage. Hydroxychloroquine sulfate crush Aug 14, 2017 Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis.. Conditions Plaquenil-related Eye Problems Eugene Eye Care. Rx Side Effects New Plaquenil Guidelines and More - American.. Most people about 90% who take antimalarial medications experience no side effects. If common side effects do occur, they are usually minor and last only for a short period of time. Please note the rare side effects listed below, specifically retinopathy, which causes damage to the eyes. Side effects associated with Plaquenil are placed in. Uncontrolled eye movements unsteadiness, trembling, or other problems with muscle control or coordination vomiting Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. Some side effects of hydroxychloroquine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.