She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine (Plaquenil) 200mg bid (6.5mg/kg) for 10 years, which was stopped one year prior to presentation. Hydroxychloroquine high blood pressure Plaquenil palpitations Inflammatory osteoarthritis plaquenil Methotrexate trexall and hydroxychloroquine plaquenil Plaquenil and Your Eyes. In some people, Plaquenil can cause a condition called hydroxychloroquine retinopathy, often referred to as bulls-eye maculopathy. The condition sometimes resembles a target, or bulls-eye ring, on the retina surrounding the macula. Hydroxychloroquine retinopathy is extremely rare and is most often seen in cases where. Published February 15, 2019 How to Succeed in Plaquenil Screenings The spectrum of OCT findings associated with the medication can make incorporating the 2016 guidelines harder than you think. Hydroxychloroquine retinopathy is characterized by a bulls eye maculopathy and is associated with corneal verticillata.2,5,6 The reported incidence of toxic retinopathy associated with chloroquine varies from 1% to 16%; there is a lesser incidence associated with hydroxychloroquine.6,8 The exact mechanism of action of hydroxychloroquine remains. Review of systems: Blurred vision, halos, dry eye, dry mouth, gastroesophageal reflux, joint pain Pupils: Reactive to light in each eye from 5 mm in the dark to 2 mm in the light. Extraocular movements: Full, both eyes (OU) Confrontation visual fields: Full OU Intra-ocular pressure The optic nerves appeared healthy with a 0.3 cup-to-disc ratio. Past Ocular History: None Medical History: Sjogren syndrome and inflammatory arthritis, supraventricular tachycardia, anxiety, depression, peptic ulcer disease Medications: prednisone, methotrexate, amitriptyline, ranitidine, estradiol, tizanidine, diltiazem, Restasis Allergies: codeine, droperidol Family History: heart disease, arthritis, cancer Social History: occasional alcohol but no tobacco or intravenous drug use. Plaquenil and diabetic retinopathy Hydroxychloroquine Plaquenil Toxicity and., How to Succeed in Plaquenil Screenings Malaria prophylaxis pregnancy chloroquineSubstitute for plaquenil Johnson and Vine examined nine patients taking a cumulative dose of hydroxychloroquine of greater than 1,000 g and noted that eight patients taking 400 mg/d had no evidence of retinopathy, whereas one patient taking more than 600 mg/d had retinopathy. 5 Bernstein concurred with this study, but noted that patients with chronic renal. Evaluation of Hydroxychloroquine Retinopathy With.. Does Patient with Lupus Have Plaquenil Retinopathy?. Hydroxychloroquine and Chloroquine Retinopathy David J.. Retinopathy can lead to sight loss so it’s important that you keep your doctor informed of any changes you experience in your vision. If you are using Plaquenil, The Wellish Vision Institute recommends regular eye exams to help catch any change that may be subtly occurring. This is the first study that focuses on assessing retinopathy risk by tracking hydroxychloroquine blood levels. Despite the benefits of treatment, which may also include anti-thrombotic and anti-diabetic effects and complete renal remission when given in combination with mycophenolate mofetil, the risks have been well documented. Jun 21, 2012 Some resources about Plaquenil hydroxychloroquine and retinopathy Screening for Hydroxychloroquine Retinopathy 08/2011 This is the American College of Rheumatology Position Statement Hydroxychloroquine Plaquenil is a commonly used medication in the management of various rheumatic diseases.