Metformin pregnancy

Discussion in 'Canada Drug' started by TXD, 31-Aug-2019.

  1. Lapo Well-Known Member

    Metformin pregnancy


    Polycystic ovarian syndrome is a common cause of anovulation and infertility in women. These women do not ovulate (release eggs) regularly and therefore have irregular menstrual periods. The ovaries have many small cysts (2-7 mm diameter) called antral follicles, giving the ovaries a characteristic "polycystic" (many cysts) appearance on ultrasound. A relatively new method of treating ovulation problems in women with polycystic ovarian disease is to use an oral medication called metformin (brand name is Glucophage). Metformin has traditionally been used as an oral drug to help control diabetes. Then, some smart doctor figured out that polycystic ovarian syndrome treatment with metformin can be very effective. If Glucophage alone does not result in ovulation and pregnancy, we often use: We also use Glucophage in women going through in vitro fertilization for PCOS, and for those with very high antral follicle counts - if their ovaries are "polycystic" by ultrasound. In order to use Medscape, your browser must be set to accept cookies delivered by the Medscape site. Medscape uses cookies to customize the site based on the information we collect at registration. The cookies contain no personally identifiable information and have no effect once you leave the Medscape site.

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    Metformin, marketed under the trade name Glucophage among others, is the first-line medication for the treatment of type 2 diabetes, particularly in people who are overweight. For those that took metformin when trying to get pregnant, there has been a concern that stopping the metformin after pregnancy is confirmed might increase the risk. Metformin is an insulin-sensitizing drug primarily used to treat diabetes, but it can also be used for fertility. Women with PCOS may benefit from taking metformin alone, along with Clomid, or even during IVF treatment.

    Metformin is an insulin-sensitizing drug primarily used to treat diabetes, but it can also be used for fertility. Women with PCOS may benefit from taking metformin alone, along with Clomid, or even during IVF treatment. Exactly how metformin improves fertility is unclear. While metformin may be used for the treatment of infertility, it is not a fertility drug. In fact, using it to treat infertility is considered an off-label use. (In other words, pregnancy achievement is not the original intended purpose of this drug.) What is this medication? To understand what metformin does, you first need to know what insulin resistance is. Insulin resistance is when the body's cells stop reacting to normal levels of insulin. As a result, the body thinks that there is not enough insulin in the system. This triggers the production of more insulin than your body needs. It's an increasingly common phenomenon: A drug that was originally synthesized for a specific purpose turns out to be effective in combating another problem. Examples include Viagra (an unsuccessful treatment for angina that succeeded as an erectile dysfunction drug) and Thalidomide, a disastrously ineffective medication for pregnancy-induced nausea that has been proven to fight bone marrow cancer [source: Brown]. Metformin can also be included in this list, but with one significant difference. Not only is it helpful in a secondary role, but it's wildly popular in treating the condition for which it was initially intended. Metformin was developed in the 1950s as a treatment for diabetes [source: Diabetes Forecast]. Today it's the most popular drug on the market for people with Type 2 diabetes [source: Science Daily]. But by 2004, Metformin was receiving international acknowledgement as a worthwhile option for patients seeking a remedy for their infertility. K.'s National Collaborating Centre for Women and Children's Health noted that the drug, when used in conjunction with other medications, improved the rate of pregnancy in women with specific infertility issues tied to ovaries containing multiple cysts [source: NCCWCH].

    Metformin pregnancy

    Metformin in Pregnancy Tied to Heavier Toddlers Medpage Today, Metformin for PCOS and Getting Pregnant - Verywell Family

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  7. Metformin is a drug that is often prescribed, off-label, for the treatment of PCOS and for regulating ovulation. It belongs to a class of drugs that improves the cells' response to insulin and regulates blood sugar.

    • Taking Metformin During Pregnancy -.
    • Metformin for PCOS and Getting Pregnant - Know More. Grow..
    • Metformin in Pregnancy - The ObG Project.

    I also have PCOS. I am 28 and tried for 3 years unsuccessfully to conceive. In Jan of 2007 I was put on Metformin I had not had a cycle since late Nov. Conclusion Metformin treatment in women with PCOS throughout pregnancy could increase the possibility of term delivery, VD and reduce the risk of EPL, preterm labor, pregnancy complications such as GDM and PIH, with no serious side effects. The first fact that any concerned pregnant mother with diabetes should know is that when using metformin during pregnancy, metformin will indeed cross over the placenta and circulate in the fetus.

     
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