Tamoxifen (Nolvadex) has been used for over 40 years to treat hormone-receptor positive early, locally advanced and metastatic breast cancers. Learn about tamoxifen and other hormone therapies for metastatic breast cancer. Hormone receptor-positive breast cancers need estrogen and/or progesterone (female hormones produced in the body) to grow. Tamoxifen attaches to the hormone receptor in the cancer cell, blocking estrogen from attaching to the receptor. This slows or stops the growth of the tumor by preventing the cancer cells from getting the hormones they need to grow. Tamoxifen is a pill taken every day for 5-10 years. For premenopausal women, tamoxifen may be combined with ovarian suppression. The benefits from tamoxifen last long after you stop taking it. Click here to refresh now (you will lose any unsaved work). To stay logged in, please refresh the page or, if you are working on a form, click on the submit button to save your work. I was started on Tamoxifen last April for DCIS after surgery and Radiation Tx. At the beginning I would have mild hot flashes throughout the day as well as night sweats during the night. I experience some mild leg cramping with the night sweats so I make sure that I drink a lot of water and don’t let myself become dehydrated. Now, I get an occasional hot flash during the day, but still have the night sweats and leg cramps nightly. I sleep with a fan blowing on me at all times and continue to hydrate and have found that this has helped me sleep a little better. And I know this sounds silly, but when I fall asleep sitting up I don’t get the night sweats, but as soon as I lay down I get them almost immediately. Duloxetine msds Safe place to buy levitra The standard treatment for men with metastatic prostate cancer is androgen. from studies in breast cancer patients receiving tamoxifen. Prostate Cancer UK Online Community Treatment Advanced or metastatic cancer Tamoxifen - a good thing? Join the online community now. Click through to become a member and gain access to support, information and real time replies. This booklet is for men who are having hormone therapy for prostate cancer. We don't know how tamoxifen affects other hormone treatments in the long term. CHICAGO — Many men with prostate cancer put off using chemotherapy as long as possible, fearing its side effects. But a new study has found that men given chemotherapy early in their treatment for advanced disease lived a median of nearly 14 months longer than those who did not get early chemotherapy. The result could upend the established treatment practice, researchers said here on Sunday.“We haven’t seen survival benefits like that for any therapy in prostate cancer,” said Dr. Morris, an associate professor at the Memorial Sloan-Kettering Cancer Center, who was not involved in the study but was selected to publicly comment on it at the annual meeting of the American Society of Clinical Oncology. Another study being presented on Sunday found that drugs called aromatase inhibitors might be better than the standard drug tamoxifen in preventing a recurrence of disease in premenopausal women with early breast cancer. Both studies are being featured in the plenary session on Sunday, meaning they were deemed among the most noteworthy of the more than 5,000 studies being presented at the meeting. Vogelzang, an author of the study on prostate cancer, said that the findings would change practice and that he had already started discussing this option with patients. In a conference that typically celebrates the latest and greatest drug, all four studies chosen for the plenary session this year are about better ways of using older drugs, showing that there can be a lot to learn even after drugs get to market. The challenge, he said, is getting men to agree.“Not many of them want to do chemotherapy, even though the numbers are convincing,” said Dr. Vogelzang, who works at the Comprehensive Cancer Centers of Nevada. Hello - I have just begun Lupron and I will eventually add an aromatase inhibitor to my mix. I started with Lupron but I am wondering why so many people take tamoxifen instead. can anyone share with me the pros and cons of each and why someone may choose one over another? I have never heard of Lupron-I took tamoxifen for 5 years. I did have to have total hystectomy from an 'enlarged' unterus (a known side effect of taxofin) about 2 1/2 yrs into taking it-after surgery/ recorey I went back on it to finish up total of 5 yrs! Denise Generally speaking, Tamoxifen is for women who are premenopausal, whereas an aromatase inhibitor (Arimidex, Femara, or Aromasin) is for women who are postmenopausal. There are some exceptions, but in general, the great dividing line is pre- vs. Premenopausal women can also opt to have regular Lupron injections to shut down their ovaries, which then makes them similar to someone who is postmenopausal, and they can take an aromatase inhibitor instead of Tamoxifen. I don't have any information as to why a premenopausal woman would choose Lupron injections over taking Tamoxifen -- taking a pill is certainly much easier than going to the doctor's office every month for an injection, and my understanding is that the injections are no fun -- but Tamoxifen does have some risks, so perhaps that's a better choice for some women with certain risk factors. Traci Yes, you're right -- I've definitely heard of some common drugs that can make Tamoxifen less effective, and many doctors recommend that women who are taking Tamoxifen avoid or try to limit taking these drugs. Tamoxifen prostate cancer Tamoxifen for Breast Cancer Treatment - Side Effects Susan., Tamoxifen - a good thing? - Prostate Cancer UK Buy accutane thailandAntabuse and vinegarCialis ratings Tamoxifen is a medication that blocks the female hormone estrogen in the body. For more than 30 years, doctors have prescribed it to fight breast cancer tumors that depend on estrogen to grow. Tamoxifen for Breast Cancer Treatment and Prevention. How hormone therapy affects you Prostate Cancer UK. Tamoxifen THE "NEW" PROSTATE CANCER INFOLINK. For more information about Tamoxifen and other hormonal therapies, read the National Cancer Institute’s, “Male Breast Cancer Treatment” and “Tamoxifen Questions and Answers”, and the American Cancer Society’s “Breast Cancer in Men”. Offer men with prostate cancer advice on how to access information and support from websites, local and national cancer information services, and from cancer support groups. 2008 1.1.4 Before choosing or recommending information resources for men with prostate cancer, check that their content is clear, reliable and up to date. Based on data from the phase III TAM-01 trial presented at the 41st Annual San Antonio Breast Cancer Symposium, investigators concluded that giving women diagnosed with breast intraepithelial neoplasia a lower dose of tamoxifen following surgery could be as effective and less toxic than the current standard dose.