Regardless of the problem, we'd like to help you find what you're looking for. I'd like to preface this by saying I haven't tested positive for anything yet so I'm unsure what kind of autoimmune disease I have, but my Rheumatologist still wants me to start on a super low dose of Plaquenil (200mg daily) to see if my symptoms improve. Plaquenil and calcium levels Plaquenil long qt Plaquenil can change the pigmentation in the skin, so it would stand to reason that it can do the same with hair. I have experienced the change in pigmentation on my legs. It looks like I have a huge bruise on the back of my leg which extends from the calf to the ankle. I call it a perma-bruise. Shalyserenee~ said. This post spoke pretty directly to me as I have both been on Plaquenil and have lost all my hair when I was originally diagnosed w Lupus 15 years ago and experienced some serious weight loss while on dialysis and thru the first few month after my kidney transplant alittle less than a year ago. Plaquenil hair loss nioxin review. and some people can handle their symptoms without medication. I originally went in to my primary doctor with what I thought. She gave me a Plaquenil pamphlet that mentioned hair bleaching, and I imagined it to be kind of nice like how people who spend time in the sun & pool get naturally lightened hair. If I see any improvements then she wants me to stay on it for life. What people lose their hair when on plaquenil Methotrexate Hair Loss When and Why It Occurs and What You Can Do, Lupus, Humor, and Wellness Growing Back that Gorgeous Head of Hair Plaquenil 200mg tablets hydroxychloroquine sulphate I saw my rheumatologist yesterday, and he said the hair loss could be from taking Plaquenil. But he said it could be from getting older. Well, the hair loss started happening about six months after I began taking the Plaquenil and over a few months I lost 40% of my hair. So it is my opinion that the hair loss cause wasn't old age but the Plaquenil. Hair Loss - General - Sjogren's Syndrome Support. Plaquenil hair loss nioxin review Sjogrens. Does plaquenil cause hair loss? -. Lupus is an autoimmune disease that causes fatigue, joint pain, joint stiffness, and a butterfly-shaped rash on the face. In addition, some people with lupus experience hair loss. Losing your hair. Taking the medication with food eases nausea for most people taking the drug. Less common side effects include skin rashes, hair thinning, and weakness. A rare side effect of Plaquenil involves visual changes or possible loss of vision—the side effect that is most worrisome for patients. The degree of hair loss/change can fluctuate depending on frequency and severity of flares, causing periods of hair loss and regrowth. Hair loss can mean the disease is progressing but is hard to determine because not every case of lupus is expressed the same in every person.