This content has not been reviewed within the past year and may not represent Web MD's most up-to-date information. To find the most current information, please enter your topic of interest into our search box. 12, 2016 (Health Day News) -- The antidepressant Effexor (venlafaxine) appears to increase a pregnant woman's risk of excess bleeding following labor, researchers say. Effexor, a serotonin-norepinephrine reuptake inhibitor (SNRI), was linked with a more than 70 percent increased risk of postpartum hemorrhage in a study of more than 300,000 Canadian pregnancies. The researchers also found that selective serotonin reuptake inhibitors (SSRIs) -- a much more commonly used class of antidepressant that includes citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac), paroxetine (Paxil) and sertraline (Zoloft) -- posed no increased risk for postpartum hemorrhage. In North America, these deaths are rare but bleeding still remains a risk for some new mothers, said study lead author Gillian Hanley, an assistant professor with the University of British Columbia's department of obstetrics and gynecology. The study findings were published in a report in the March issue of Obstetrics & Gynecology Excessive bleeding after labor accounts for nearly one-quarter of all pregnancy-related deaths worldwide, according to the U. "A severe hemorrhage could result in an emergency operation to stop the bleeding, and often may result in blood transfusions," Hanley said. Complications can include shock, organ failure, infection and dangerous blood clots, according to the AHRQ. About 5 percent of American and Canadian women use antidepressants at some point during their pregnancy, according to background information with the study, and there has been some concern that these medications increase bleeding risk for mothers. It’s taken me a long time to sit down and write this post. I think it’s just difficult to relive those few months after Story’s birth. Not that I’m not aware of my struggle with postpartum depression and anxiety every day. I am such an open book when the topic comes up because one of my goals is to not only increase awareness, but to normalize PPD and PPA. I couldn’t get Story settled, but I didn’t want to wake Seth because I knew at least one of us needed to get a good night’s rest. Story was such a content baby, rarely making a fuss. I am thankful that I had the necessary support to get through to the other side. I didn’t wake my mom either because I felt like I should somehow know what Story needed or like I was really the only one who could help her. At 5am, my mom woke up and quickly ushered me to bed. I remember looking at Story and feeling like I didn’t have the physical strength to pick her up. But I just felt like I didn’t have the tools to care for her and I was terrified that her precious little life was in my hands. If I can help save one life by sharing my story, it’s worth it. When I woke up 3 hours later, that was the first time I remember that anxious feeling – my heart was racing as I jumped out of bed to make sure that Story was okay. I recall saying something to Susy along the lines of “I feel like I might have made a mistake.” The fear that I had entered into parenthood before I was ready gripped me like a vice. I literally felt like I had walked into a season of life I wasn’t prepared for. The worst was when she started to lose weight – this was after she had a gain after her initial loss upon coming home from the hospital. As I wrote in a previous post, Story’s birth didn’t go as I had hoped or planned. Sure enough, she was perfectly content in my mom’s arms, but I couldn’t get myself to fully relax. Our dear friends Scott and Susy came over to see Story and check in on us. The doctor suggested that I begin supplementing with formula. I was her mother, the one that was supposed to be providing her with the nutrition she needed to grow and thrive, and I couldn’t even do that. Susy ended up writing Seth an email after they had been at our house.
I want to know before I start taking it have any of you ladies had any side effects from it? does it make you feel 'out of it' or does it relax you? and the main question has it really helped you out? I was reslly afraid to talk to the dr about it as it is embarrassing I did not tell him everything that I am going through, but a least he gave me something thanks for any information ps I did not tell my ob about this when i went in for my 6 week pp check up cause i was to ashamed to talk about it with her was 2 weeks. My Dr suggested that I take it at night bc it can make you sleepy. I felt the meds really kick about a week after it was in my system. It gave me a strange feeling in my jaw, and insomnia.. I haven't had any side effects except the morning after my first night taking it I felt a little nauseous. I ultimately stopped taking it because of the insomnia. Supposedly it goes away after a few weeks (not everyone has it to begin with). I'm now trying to get up the courage to call and ask for something that used more for acute anxiety. I'm embarassed and afraid they'll think I just want drugs for some reason. I always took it in the morning, maybe I should try at night.. I mean, I guess I felt sleepy while taking it, but I assumed that was due to no sleep.. These highlights do not include all the information needed to use ZOLOFT safely and effectively. ZOLOFT (sertraline hydrochloride) tablets, for oral use ZOLOFT (sertraline hydrochloride) oral solution Initial U. Approval: 1991Most common adverse reactions (≥5% and twice placebo) in pooled placebo-controlled MDD, OCD, PD, PTSD, SAD and PMDD clinical trials were nausea, diarrhea/loose stool, tremor, dyspepsia, decreased appetite, hyperhidrosis, ejaculation failure, and decreased libido (6.1) Antidepressants increased the risk of suicidal thoughts and behavior in pediatric and young adult patients in short-term studies. Closely monitor all antidepressant-treated patients for clinical worsening, and for emergence of suicidal thoughts and behaviors The recommended initial dosage and maximum ZOLOFT dosage in patients with MDD, OCD, PD, PTSD, and SAD are displayed in Table 1 below. A dosage of 25 mg or 50 mg per day is the initial therapeutic dosage. For adults and pediatric patients, subsequent dosages may be increased in case of an inadequate response in 25 to 50 mg per day increments once a week, depending on tolerability, up to a maximum of 200 mg per day. Given the 24-hour elimination half-life of ZOLOFT, the recommended interval between dose changes is one week. The recommended starting ZOLOFT dosage in adult women with PMDD is 50 mg per day. ZOLOFT may be administered either continuously (every day throughout the menstrual cycle) or intermittently (only during the luteal phase of the menstrual cycle, i.e., starting the daily dosage 14 days prior to the anticipated onset of menstruation and continuing through the onset of menses).
Feb 12, 2016. This Antidepressant Linked to Postpartum Bleeding. Paxil and sertraline Zoloft -- posed no increased risk for postpartum hemorrhage. Sertraline vs Bupropion for Anxiety. None of Wellbutrin® formulations are licensed for anxiety disorders. Zoloft® is indicated for several anxiety disorders, including panic attacks, social anxiety, obsessive-compulsive disorder.