Traditional antidepressants are considered "experimental" for treating bipolar depression in that none has been proven to be more effective than a placebo (sugar pill) in bipolar I disorder. Studies also have shown that they may not provide additional benefit for bipolar depression if they're are taken along with with a mood stabilizer such as lithium or Depakote. Nevertheless, your doctor may prescribe newer antidepressants known as SSRIs (selective serotonin reuptake inhibitors) for treating depression in bipolar disorder -- along with lithium or other mood stabilizing drugs such as valproate, carbamazepine or an atypical antipsychotic. If and when an antidepressant is effective for someone with bipolar depression, it is believed that the medicine works by boosting the functioning of nerve cells in the brain that communicate through the chemical (neurotransmitter) serotonin. This class of antidepressants includes: Vilazodone (Viibryd) and vortioxetine (Trintellix, formerly called Brintellix) are two newer antidepressants that affect the serotonin transporter as well as other serotonin receptors in the brain. Most antidepressants take several weeks to start working. Though the first one that is prescribed works in the majority of people, others may need to try two or three to find the right one. I confronted this question last September, when I had breakfast with one of psychiatry's leading scholars and administrators. He was complaining about the influence of pharmaceutical houses on physicians. Why, he asked, did doctors prescribe the newer antipsychotics, like Abilify and Zyprexa, when studies showed that older and much cheaper drugs, like Trilafon and Haldol, were just as effective? I told my colleague that I shared his concern about the influence of drug companies, but I thought that clinicians had a tough choice. The side effects of the medications were so different that the new and old medications were finally not identical. All right, the colleague said, but what about antidepressants? Almost all those medications are available as generics, but at a disproportionate rate, doctors prescribe the one antidepressant that still has patent protection, Lexapro.
The largest trial of its kind, STAR*D (Sequenced Treatment Alternatives to Relieve Depression) followed 3,671 patients, most of whom had suffered from depression for years, as they tried a sequence of treatments that were closely supervised by their own doctors. "Unlike previous studies that had strict inclusion criteria, the focus of our research now is on real-world practices so that the results will be of practical use," says Thomas Insel, MD, director of the National Institute of Mental Health, which sponsored the study. Participants were first put on the antidepressant Celexa for 12 to 14 weeks. Those whose symptoms cleared up or improved significantly entered a yearlong follow-up phase. Others had three options: switching to a new drug (Wellbutrin, Effexor, or Zoloft), remaining on Celexa and adding another drug (Wellbutrin or Bus Par) or cognitive therapy, or trying the therapy alone. The third and fourth phases let patients try other antidepressants, such as Pamelor or Remeron. The results: One-third of depressed patients, the study indicates, will not get better—symptom free—even with up to four treatment attempts. Zoloft vs Celexa Depression is said to be a state of sadness not in an acute time but in a longer time. A death of a family member, being heartbroken, or even failures in life make people depressed for some time. If this continues for such a long time, it is not already just sadness but rather depression. Two drugs that aim to secrete happy hormones are Zoloft and Celexa. Let us compare the differences between these two drugs. The generic name of Zoloft is Sertraline while the generic name of Celexa is Citaprolam. Both Zoloft and Celexa are SSRIs or selective serotonin reuptake inhibitors. Celexa was created during 1989 by the Lundbeck pharmaceutical company. Pfizer manufactured it under its chemist, Reinhard Sarges.
Celexa (citalopram) is good for treating depression and anxiety. Side effects are less likely to happen compared to other antidepressants; however, it is not the best choice for people with heart or liver problems. Celexa is an effective antidepressant but it may cause more side effects than other SSRIs, such as escitalopram. Prescribed for Anxiety and Stress, Depression, Postpartum Depression. Celexa may also be used for purposes not listed in this medication guide. " Celexa is an effective antidepressant but it may cause more side effects than other SSRIs, such as escitalopram. Prescribed for Anxiety and Stress, Depression, Postpartum Depression. more Zoloft is an effective antidepressant with less potential for drowsiness than many other antidepressants. Best wishes I'm a 31 year old Male who has had challenges with depression and anxiety throughout my life. Prescribed for Depression, Panic Disorder, Major Depressive Disorder, Social Anxiety Disorder, Obsessive Compulsive Disorder, Post Traumatic Stress Disorder, Postpartum Depression, Premenstrual Dysphoric Disorder. I have NOT lost my temper from being stressed out for 6 years. The cons are it made me not very motivated, felt kind of numb to strong feelings. I wouldn’t take it again for years bc it blocked my clear perspective. Things that really help but can’t completely replace anti dep is fish oil, vit d, exercise, sunlight, folate like spinach , lentils really good. I have been on several different meds in my past, including lexapro, paxil, effexor, wellbutrin, prozac, zoloft, and some others as well. Zoloft may also be used for purposes not listed in this medication guide. I like most people think I am feeling better and have tried to wean myself off Celexa 3 times in the past 6 years but I never make it past 2 weeks before I start having meltdowns. Of all of these meds, I've found zoloft works the best for me.
Side effects of Celexa that are different from Zoloft include increased sweating or urination, and cold symptoms such as stuffy nose, sneezing. The generic name of Zoloft is Sertraline while the generic name of Celexa is Citaprolam. Both Zoloft and Celexa are SSRIs or selective.