Prednisone is a corticosteroid that can be used to treat conditions and diseases such as asthma, allergies and arthritis. However, when prescribing this medication, the prednisone side effects should also be considered, as these may cause a lot of damage if administered as a long term treatment. Among the synthetic corticosteroids, prednisone is one of the most widely used and most effective drugs. Prednisone is an immunity suppressor that also has analgesic and anti-inflammatory properties. The most common uses of prednisone include: Prednisone may be replaced by prednisolone or hydrocortisone. Dogs that get prednisone as a short term treatment (i.e. However, if the treatment is lengthy, prednisone may cause a number of side effects, including: Prednisone should not be prescribed for canines with stomach problems such as ulcers or for dogs with systemic fungal infections. Puppies under the age of 6 months, pregnant or lactating mothers must stay away from prednisone or other corticosteroids, as prednisone slows down the immune system and its function is essential in these times. Prednisone is an anti-inflammatory drug that is classified as a glucocorticosteroid - a class of endogenous hormones that are produced by the adrenal gland in the human body. Glucocorticosteroids (or glucocorticoids) are stress hormones that aim to prepare the body to respond to infections, diseases and other stressful events like surgery, accidents and even pain caused by the withdrawal of certain medications etc. Prednisone is a synthetic form of glucocorticoid that is mainly prescribed for therapeutic reasons to minimize the intensity of inflammatory or autoimmune reactions in the body and is not generally considered a drug of abuse. However, surprisingly, abrupt cessation of therapy is associated with moderate to severe withdrawal symptoms. The intensity or severity of symptoms is dependent on the duration of therapy, underlying medical conditions and dosage frequency of prednisone. Withdrawal symptoms can include: In some susceptible patients, abrupt prednisone withdrawal may also lead to severe complications like acute adrenal crisis, which is a life-threatening condition that is marked by high grade fever, excessive sweating, changes in the complexion of skin, low blood pressure, dehydration, abdominal pain, flank pain, joint pain, changes in heart rate, rigors and shaking chills - ultimately culminating in confusion, delirium and coma or even death. The human body is very sensitive and calculated when it comes to the maintenance of its internal environment, so in situations where we consume glucocorticoids from external sources (like prednisone), the human adrenal glands shut down the production of glucocorticoids.
The side effects of a Prednisone shot may be mild and treatable, or lead to severe and long-term medical problems. Every patient should educate themselves about the probable side effects before starting any medication. Prednisone is a popular drug recommended by doctors for treating a wide range of medical conditions. Its primary therapeutic effect is to reduce the body's immune responses, and is administered after organ transplantation. Sold under the brand names Prednicen-M, Deltasone, Liquid Pred, and Orasone, Prednisone shows varied side effects in patients. Chemically, it is a synthetic glucocorticoid, classified under the class steroid or corticosteroid. When delivered in the body, it mimics hydrocortisone hormone, which is secreted by the adrenal glands. It is administered in the form of oral tablets, oral solution, and shots. Marcy Brinkley has been writing professionally since 2007. Her work has appeared in "Chicken Soup for the Soul," "Texas Health Law Reporter" and the "State Bar of Texas Health Law Section Report." Her degrees include a Bachelor of Science in Nursing; a Master of Business Administration; and a Doctor of Jurisprudence. View Full Profile Animal studies have shown an increased risk of cleft lip, a birth defect, in rats, mice and rabbits when the mother received prednisone or other corticosteroids during pregnancy. However, a human study conducted in Spain found that although the risk of cleft lip was six times higher in infants whose mothers took corticosteroids during the first trimester than in the control group, the actual number of cleft lip cases was only two out of 1,184 infants compared to the expected rate of 0.2, according to Dr. Elvira Rodríguez-Pinilla in an article published in the July 1998 issue of "Teratology." If you take prednisone and become pregnant, discuss the matter with your health care provider. If you stop prednisone suddenly, you may experience dizziness, low blood pressure, low blood sugar and difficulty breathing. Researchers have concluded that the fetus may be protected from adverse effects of prednisone for several reasons: because the placenta makes the drug inactive; the drug binds to a large protein, preventing prednisone from crossing the placental barrier; and the baby's liver cannot activate the drug until the second trimester of pregnancy, according to Reproductive Immunology Associates.
The side effects of a Prednisone shot may be mild and treatable, or lead to severe and long-term medical problems. Every patient should educate themselves about the. Prednisone learn about side effects, dosage, special precautions, and more on MedlinePlus