Hello all, I learned something very valuable this week that I wanted to share in case someone else is in this situation. I'm 47, married, with 4 kids, and I occasionally (once or twice a year) get an e-coli UTI. Like most of you, I know what they feel like, can tell when I have one, and they're horrible so I immediately go to the doctor to get treatment. Went to my family doctor, did the in-office dipstick test, tested positive for leukocytes & blood. So they did, and the "best" antibiotic for my e-coli infection was listed as Levaquin. I agreed to go on it, even though I've heard scary things about that family of antibiotics. I was desperate, the pain was awful.10 days on Levaquin, and it took until day #9 before I felt like the symptoms were mostly gone. Finished up the 10 day course, and within 2 days, symptoms were back with a vengeance. So my doctor said I "must not really have an infection." Well, I know what a UTI feels like, and I was VERY certain that it was not gone. So my family doctor gave me a much higher dose of Levaquin for 5 more days. I badgered doctor into letting me try Macrobid for 7 days, because I truly felt the Levaquin wasn't working for me for some reason. Because this is a personal blog, I hope you will indulge me for a moment as I make what is, to me anyway, a very important announcement about my life. I am purchasing nothing but baseball ties from here on in. They were the sort of people who belonged to country clubs and drank champagne from crystal tulip glasses and clicked croquet balls through those hoopy things stuck into the ground and they all had spouses named “Lovey” like Thurston Howell III. It’s red and has a bunch of little sketches of the proper way to hold the baseball when throwing different pitches. It’s one that features the Norman Rockwell painting of the umpires deciding to call the game because of rain. From this day forward, I intend to only wear baseball ties. I’m sure this has happened to you — for years, I have thought about making this transition to an all baseball tie wardrobe, but the time was never quite right. On those rare days when my father wore a tie, you knew something big and vital was about to happen — someone was about get married, someone had just passed away, the factory was having the big Christmas party at the owner’s house. There’s the knuckleball grip, the slider grip, the palmball grip (palmball! For years, I wore real ties — “real” meaning “ties that do not necessarily have baseballs on them” — and it was fine. It’s actually called “Game Called Because of Rain.” I had to get that tie, it was way cool. Yes, sure, first thing you will say is: “Wait, you’re going to wear a BASEBALL TIE to a somber event like a funeral or the dinner when you accept the National Book Award for your soon to be finished book on Harry Houdini? The hope was that I would become a doctor, naturally. The everything-must-go-store-closing settlement was accountant. In my mind, men who wore ties to work, wow, they were rich and powerful. and I was in the gift shop, and I saw this awesome baseball tie. I wore a different baseball tie every day until I ran out (I think I have 11 of them now) and then started over. I began this all-baseball-tie process last October during the baseball playoffs. There was a clear, “We sacrifice so that you will have a better life” theme throughout my childhood. I didn’t know many men who wore ties to work; they mostly did not live in our neighborhood. Back to how this happened: Last year I was at the Baseball Hall of Fame for this incredibly cool project that I can’t wait to tell you about … So during the playoffs last year, I made the switch. I mean, people noticed individual ties — partiparticularly Norman Rockwell one which seems to be the most beloved of the group so far — but nobody noticed that I was wearing only baseball ties. Also, I am in the market for baseball ties that will fit all occasions. My parents are immigrants who came to America just three years before I was born. My mother stayed at home (though she later went back to school and became a computer programmer). It’s hard to describe the power of suits and ties in my childhood imagination. Seriously, who am I trying to impress at this point in my life? What a great group, and before it began I went to see the delightful Andrea Thome, Jim’s wife, who my wife and I got to know many years ago. I work in a profession where you really don’t have to wear a tie, and I do anyway. I have theorized — because, honestly, it’s just a theory — that the reason I wear a jacket and tie is that my parents always hoped that I would have a jacket-and-tie kind of job. well, just today, I went to the Hall of Fame press conference for Jim Thome, Chipper Jones, Vladimir Guerrero and Trevor Hoffman. I will readily admit that my midlife crisis does not have the same energy as the convertible sports-car midlife crisis, but that’s OK. I am like the opposite of the cool executive and creative types you read about who brag about how they love their job precisely because they don’t have to wear a tie. I think back to my younger self, the kid who wanted to make a success of his life but had neither the will nor the brains to do it the conventional way, and I would love to tell him that I have a job where I wear jackets and ties. “Cool,” he would say or whatever the word was at that time.
Fluoroquinolone antibiotic ciprofloxacin (Cipro) is widely used to treat Urinary Tract Infections (UTIs) because it reaches high urinary concentrations, has an excellent activity against most uropathogens, and is available in oral and intravenous formulations. The e Xt Ra study  found that more than a third of the women taking Cipro XR (ciprofloxacin extended-release) for the treatment of uncomplicated urinary tract infections get significant improvement within just 3 hours of taking the antibiotic and half of the women reported symptom improvement within 6 hours. Ciprofloxacin may fail to cure urinary infection caused by resistant bacteria. Ciprofloxacin dosage for UTI Children 1–17 years of age: Complicated UTIs and pyelonephritis: 10-20 mg/kg (up to 750 mg) every 12 hours for 10-21 days. Additionally, 87% reported significant symptom improvement and 22% reported complete relief within 24 hours. Research indicates emerging ciproﬂoxacin resistance among bacteria causing urinary tract infections. coli resistant to ciprofloxacin account for about 17% . Adults: Cystitis (bladder indection): 250 mg every 12 hours for 3 days. Cipro XR: 500 mg once daily for 3 days, preferably given with the evening meal. Mild to moderate UTIs: The standard dose is 250 mg every 12 hours for 7-14 days. Complicated UTIs, pyelonephritis: 500 mg every 12 hours for 7-14 days. Check out this alternative antibiotic options: Top 5 Recommended Antibiotics For UTI. Fluoroquinolones work by preventing bacterial DNA from unwinding and duplicating. It is a broad-spectrum antibiotic (effective for both gram-negative and gram-positive bacteria). The Infectious Diseases Society of America recommends fluoroquinolones for: Cipro has been on the market for over 25 years and this might be why physicians still casually prescribe it. For example, when ordering Cipro for UTI treatment my doctor did not spend much time to explain potential dangers. Since majority will tolerate this drug well (only 0.2%-0.4% of patients develop serious side-effects) most doctors might never encounter the devastating results of their treatment decision. However when they do happen the adverse effects are serious, long-term, and often permanent.
Answers question resolved - Posted in cipro, urinary tract infection, infections - Answer This doesnt mean the Cipro isnt working. Keep taking. Efficacy Levofloxacin Levaquin 750 mg once-daily for 7 days is as effective as ciprofloxacin 500 mg twice-daily for 10 days in the treatment of UTI. A study by Peterson compared levofloxacin versus ciprofloxacin in the treatment of complicated urinary tract infections and acute pyelonephritis4.