Major Depressive Disorder–ZOLOFT (sertraline hydrochloride) is indicated for the treatment of major depressive disorder in adults. The efficacy of ZOLOFT in the treatment of a major depressive episode was established in six to eight week controlled trials of adult outpatients whose diagnoses corresponded most closely to the DSM-III category of major depressive disorder (see Clinical Trials under CLINICAL PHARMACOLOGY). A major depressive episode implies a prominent and relatively persistent depressed or dysphoric mood that usually interferes with daily functioning (nearly every day for at least 2 weeks); it should include at least 4 of the following 8 symptoms: change in appetite, change in sleep, psychomotor agitation or retardation, loss of interest in usual activities or decrease in sexual drive, increased fatigue, feelings of guilt or worthlessness, slowed thinking or impaired concentration, and a suicide attempt or suicidal ideation. The antidepressant action of ZOLOFT in hospitalized depressed patients has not been adequately studied. The efficacy of ZOLOFT in maintaining an antidepressant response for up to 44 weeks following 8 weeks of open-label acute treatment (52 weeks total) was demonstrated in a placebo-controlled trial. The usefulness of the drug in patients receiving ZOLOFT for extended periods should be reevaluated periodically (see Clinical Trials under CLINICAL PHARMACOLOGY). Obsessive-Compulsive Disorder–ZOLOFT is indicated for the treatment of obsessions and compulsions in patients with obsessive-compulsive disorder (OCD), as defined in the DSM-III-R; i.e., the obsessions or compulsions cause marked distress, are time-consuming, or significantly interfere with social or occupational functioning. For people with depression and other mental health issues, medication can offer welcome relief. One drug commonly used to treat depression is Zoloft. Zoloft is a prescription drug that belongs to a class of antidepressants called selective serotonin reuptake inhibitors (SSRIs). Like other SSRIs, this medication works by changing how your brain cells reabsorb the neurotransmitter serotonin. If your doctor gives you this medication, you may wonder if it’s safe to drink alcohol during treatment. Read on to learn why mixing alcohol with Zoloft is not recommended. We’ll also explain the impact alcohol can have on your depression with or without medication.
If you are on a personal connection, like at home, you can run an anti-virus scan on your device to make sure it is not infected with malware. If you are at an office or shared network, you can ask the network administrator to run a scan across the network looking for misconfigured or infected devices. When you take a prescription medication, particularly one that’s intended for long-term use, it’s important to be aware of any possible interactions, effects, and reactions that may come with its use. One example of a long-term medication that’s commonly prescribed is Zoloft. Zoloft is a prescription anti-depressant, and people frequently wonder how it might interact with other substances or what the potential side effects may be. Below is more information about one substance in particular: marijuana. There are details about the possibility of marijuana and Zoloft interactions, effects & reactions. Before reviewing marijuana and Zoloft interactions, effects & reactions, what is Zoloft? Zoloft is a prescription medicine that’s primarily used to treat depression, but it has other uses as well.
Table 5. Clinically-Significant Drug Interactions with ZOLOFT. Monoamine Oxidase Inhibitors MAOIs. Clinical Impact The concomitant use of SSRIs including. Medications are known to interact with Zoloft. Includes tramadol, aspirin, trazodone.